The HMGB, or high mobility group box proteins in our antibody catalog are used in a variety of research areas, predominantly histone, chromatin and transcription research.

Antibody suppliers to cancer research groups commonly list BRAF on their antibody database. A gene which encodes the B-Raf cell-signalling protein, it plays an important role in cell division, growth and secretion.

Antibody research is conducted for all sorts of clinical reasons – such as finding a cure for short-sightedness. Also known as myopia, short-sightedness is one of the commonest eye conditions in the world. It is thought to be largely inherited, but antibody studies have so far failed to reveal a definite genetic link.

Antibodies don’t usually make the news headlines; when they do, it’s sometimes for the simplest of reasons. Such was the case recently, when an antibody study looking at levels of homocysteine in human volunteers over a two-year period revealed a possible new treatment for Alzheimer’s Disease – humble vitamin B. Homocysteine is a simple homologue of the amino acid cysteine, expressed throughout the body.

Clinical research is highly dependent on antibody suppliers being able to provide high-quality products targeted to the proteins causing disease.

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